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The mechanism of membrane-associated steps in tail-anchored protein insertion

Tail-anchored (TA) membrane proteins destined for the endoplasmic reticulum are chaperoned by cytosolic targeting factors that deliver them to a membrane receptor for insertion. While a basic framework for TA protein recognition is now emerging, the decisive targeting and membrane insertion steps ar...

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Detalhes bibliográficos
Main Authors: Mariappan, Malaiyalam, Mateja, Agnieszka, Dobosz, Malgorzata, Bove, Elia, Hegde, Ramanujan S., Keenan, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760497/
https://ncbi.nlm.nih.gov/pubmed/21866104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10362
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