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A Ribosome-Associating Factor Chaperones Tail-Anchored Membrane Proteins
Hundreds of proteins are post-translationally inserted into the endoplasmic reticulum (ER) membrane by a single carboxy-terminal transmembrane domain (TMD)1. During targeting through the cytosol, the hydrophobic TMD of these tail-anchored (TA) proteins requires constant chaperoning to prevent aggreg...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928861/ https://ncbi.nlm.nih.gov/pubmed/20676083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09296 |
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