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Tail-anchored membrane protein insertion into the endoplasmic reticulum

Membrane proteins are inserted into the endoplasmic reticulum by two highly conserved parallel pathways. The well-studied co-translational pathway uses the signal recognition particle and its receptor for targeting, and the Sec61 translocon for membrane integration. A recently discovered post-transl...

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Detalles Bibliográficos
Autores principales: Hegde, Ramanujan S., Keenan, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760496/
https://ncbi.nlm.nih.gov/pubmed/22086371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3226
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