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Transmembrane topogenesis of a tail-anchored protein is modulated by membrane lipid composition
A large class of proteins with cytosolic functional domains is anchored to selected intracellular membranes by a single hydrophobic segment close to the C-terminus. Although such tail-anchored (TA) proteins are numerous, diverse, and functionally important, the mechanism of their transmembrane inser...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1176458/ https://ncbi.nlm.nih.gov/pubmed/15973434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600730 |
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