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The Mechanism of Tail Anchored Protein Insertion into the ER Membrane
Tail-anchored (TA) proteins access the secretory pathway via posttranslational insertion of their C-terminal transmembrane domain into the endoplasmic reticulum (ER). Get3 is an ATPase that delivers TA proteins to the ER by interacting with the Get1-Get2 transmembrane complex but how Get3’s nucleoti...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3614002/ https://ncbi.nlm.nih.gov/pubmed/21835666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.07.020 |
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