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A Chaperone Cascade Sorts Proteins for Posttranslational Membrane Insertion into the Endoplasmic Reticulum

Tail-anchored (TA) proteins are posttranslationally inserted into either the endoplasmic reticulum (ER) or the mitochondrial outer membrane. The C-terminal transmembrane domains (TMDs) of TA proteins enable their many essential cellular functions by specifying the membrane target, but how cells proc...

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Main Authors: Wang, Fei, Brown, Emily C., Mak, Gary, Zhuang, Jimmy, Denic, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652556/
https://ncbi.nlm.nih.gov/pubmed/20850366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.08.038
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