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Guiding tail-anchored membrane proteins to the endoplasmic reticulum in a chaperone cascade
Newly synthesized integral membrane proteins must traverse the aqueous cytosolic environment before arrival at their membrane destination and are prone to aggregation, misfolding, and mislocalization during this process. The biogenesis of integral membrane proteins therefore poses acute challenges t...
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| Publicado no: | J Biol Chem |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6851334/ https://ncbi.nlm.nih.gov/pubmed/31575659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.006197 |
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