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Guiding tail-anchored membrane proteins to the endoplasmic reticulum in a chaperone cascade

Newly synthesized integral membrane proteins must traverse the aqueous cytosolic environment before arrival at their membrane destination and are prone to aggregation, misfolding, and mislocalization during this process. The biogenesis of integral membrane proteins therefore poses acute challenges t...

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Vydáno v:J Biol Chem
Hlavní autor: Shan, Shu-ou
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851334/
https://ncbi.nlm.nih.gov/pubmed/31575659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.006197
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