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A microbial expression system for high-level production of scFv HIV-neutralizing antibody fragments in Escherichia coli
Monoclonal antibodies (mABs) are of great biopharmaceutical importance for the diagnosis and treatment of diseases. However, their production in mammalian expression hosts usually requires extensive production times and is expensive. Escherichia coli has become a new platform for production of funct...
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| Publié dans: | Appl Microbiol Biotechnol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Berlin Heidelberg
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6851033/ https://ncbi.nlm.nih.gov/pubmed/31641814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-019-10145-1 |
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