Genetic heterogeneity in response to adenovirus gene therapy

Por Lefesvre, Pierre, Attema, Joline, Lemckert, Angelique, Havenga, Menzo, Bekkum, Dirk van
Publicado em 2003

The Distal Short Consensus Repeats 1 and 2 of the Membrane Cofactor Protein CD46 and Their Distance from the Cell Membrane Determine Productive Entry of Species B Adenovirus Seroty...

Por Fleischli, Christoph, Verhaagh, Sandra, Havenga, Menzo, Sirena, Dominique, Schaffner, Walter, Cattaneo, Roberto, Greber, Urs F., Hemmi, Silvio
Publicado em 2005

Myeloid and Plasmacytoid Dendritic Cells Are Susceptible to Recombinant Adenovirus Vectors and Stimulate Polyfunctional Memory T Cell Responses

Por Loré, Karin, Adams, William C., Havenga, Menzo J.E., Precopio, Melissa L., Holterman, Lennart, Goudsmit, Jaap, Koup, Richard A.
Publicado em 2007

Trafficking of Antigen-Specific CD8+ T-Lymphocytes to Mucosal Surfaces Following Intramuscular Vaccination

Por Kaufman, David R., Liu, Jinyan, Carville, Angela, Mansfield, Keith G., Havenga, Menzo J.E., Goudsmit, Jaap, Barouch, Dan H.
Publicado em 2008

Development of Novel Adenoviral Vectors to Overcome Challenges Observed With HAdV-5–based Constructs

Por Alonso-Padilla, Julio, Papp, Tibor, Kaján, Győző L, Benkő, Mária, Havenga, Menzo, Lemckert, Angelique, Harrach, Balázs, Baker, Andrew H
Publicado no Mol Ther (2016)

Common Structure of Rare Replication-Deficient E1-Positive Particles in Adenoviral Vector Batches

Por Murakami, Pete, Havenga, Menzo, Fawaz, Farah, Vogels, Ronald, Marzio, Giuseppe, Pungor, Erno, Files, Jim, Do, Linh, Goudsmit, Jaap, McCaman, Michael
Publicado em 2004

Avidity Binding of Human Adenovirus Serotypes 3 and 7 to the Membrane Cofactor CD46 Triggers Infection

Por Trinh, Hung V., Lesage, Guillaume, Chennamparampil, Venus, Vollenweider, Benedikt, Burckhardt, Christoph J., Schauer, Stefan, Havenga, Menzo, Greber, Urs F., Hemmi, Silvio
Publicado em 2012

Quantifying Adenovirus-Neutralizing Antibodies by Luciferase Transgene Detection: Addressing Preexisting Immunity to Vaccine and Gene Therapy Vectors

Por Sprangers, Mieke C., Lakhai, Wandena, Koudstaal, Wouter, Verhoeven, Marielle, Koel, Björn F., Vogels, Ronald, Goudsmit, Jaap, Havenga, Menzo J. E., Kostense, Stefan
Publicado em 2003

Targeting of Adenovirus Serotype 5 (Ad5) and 5/47 Pseudotyped Vectors In Vivo: Fundamental Involvement of Coagulation Factors and Redundancy of CAR Binding by Ad5

Por Waddington, Simon N., Parker, Alan L., Havenga, Menzo, Nicklin, Stuart A., Buckley, Suzanne M. K., McVey, John H., Baker, Andrew H.
Publicado em 2007

Macropinocytotic Uptake and Infection of Human Epithelial Cells with Species B2 Adenovirus Type 35

Por Kälin, Stefan, Amstutz, Beat, Gastaldelli, Michele, Wolfrum, Nina, Boucke, Karin, Havenga, Menzo, DiGennaro, Fabienne, Liska, Nicole, Hemmi, Silvio, Greber, Urs F.
Publicado em 2010

Immunogenicity of Heterologous Recombinant Adenovirus Prime-Boost Vaccine Regimens Is Enhanced by Circumventing Vector Cross-Reactivity

Por Thorner, Anna R., Lemckert, Angelique A. C., Goudsmit, Jaap, Lynch, Diana M., Ewald, Bonnie A., Denholtz, Matthew, Havenga, Menzo J. E., Barouch, Dan H.
Publicado em 2006

Adenoviruses Activate Human Dendritic Cells without Polarization toward a T-Helper Type 1-Inducing Subset

Por Rea, Delphine, Schagen, Frederik H. E., Hoeben, Rob C., Mehtali, Majid, Havenga, Menzo J. E., Toes, Rene E. M., Melief, Cornelis J. M., Offringa, Rienk
Publicado em 1999

Influence of Coagulation Factor Zymogens on the Infectivity of Adenoviruses Pseudotyped with Fibers from Subgroup D

Por Parker, Alan L., McVey, John H., Doctor, Jessica H., Lopez-Franco, Oscar, Waddington, Simon N., Havenga, Menzo J. E., Nicklin, Stuart A., Baker, Andrew H.
Publicado em 2007

Impact of Recombinant Adenovirus Serotype 35 Priming versus Boosting of a Plasmodium falciparum Protein: Characterization of T- and B-Cell Responses to Liver-Stage Antigen 1

Por Rodríguez, Ariane, Goudsmit, Jaap, Companjen, Arjen, Mintardjo, Ratna, Gillissen, Gert, Tax, Dennis, Sijtsma, Jeroen, Weverling, Gerrit Jan, Holterman, Lennart, Lanar, David E., Havenga, Menzo J. E., Radošević, Katarina
Publicado em 2008

Magnitude and Phenotype of Cellular Immune Responses Elicited by Recombinant Adenovirus Vectors and Heterologous Prime-Boost Regimens in Rhesus Monkeys

Por Liu, Jinyan, Ewald, Bonnie A., Lynch, Diana M., Denholtz, Matthew, Abbink, Peter, Lemckert, Angelique A. C., Carville, Angela, Mansfield, Keith G., Havenga, Menzo J., Goudsmit, Jaap, Barouch, Dan H.
Publicado em 2008

Effect of Neutralizing Sera on Factor X-Mediated Adenovirus Serotype 5 Gene Transfer

Por Parker, Alan L., Waddington, Simon N., Buckley, Suzanne M. K., Custers, Jerome, Havenga, Menzo J. E., van Rooijen, Nico, Goudsmit, Jaap, McVey, John H., Nicklin, Stuart A., Baker, Andrew H.
Publicado em 2009

Differential Antigen Requirements for Protection against Systemic and Intranasal Vaccinia Virus Challenges in Mice

Por Kaufman, David R., Goudsmit, Jaap, Holterman, Lennart, Ewald, Bonnie A., Denholtz, Matthew, Devoy, Colleen, Giri, Ayush, Grandpre, Lauren E., Heraud, Jean-Michel, Franchini, Genoveffa, Seaman, Michael S., Havenga, Menzo J. E., Barouch, Dan H.
Publicado em 2008

Protective Immune Responses to a Recombinant Adenovirus Type 35 Tuberculosis Vaccine in Two Mouse Strains: CD4 and CD8 T-Cell Epitope Mapping and Role of Gamma Interferon

Por Radošević, Katarina, Wieland, Catharina W., Rodriguez, Ariane, Weverling, Gerrit Jan, Mintardjo, Ratna, Gillissen, Gert, Vogels, Ronald, Skeiky, Yasir A. W., Hone, David M., Sadoff, Jerald C., van der Poll, Tom, Havenga, Menzo, Goudsmit, Jaap
Publicado em 2007

Immunogenicity of Heterologous Prime-Boost Regimens Involving Recombinant Adenovirus Serotype 11 (Ad11) and Ad35 Vaccine Vectors in the Presence of Anti-Ad5 Immunity

Por Lemckert, Angelique A. C., Sumida, Shawn M., Holterman, Lennart, Vogels, Ronald, Truitt, Diana M., Lynch, Diana M., Nanda, Anjali, Ewald, Bonnie A., Gorgone, Darci A., Lifton, Michelle A., Goudsmit, Jaap, Havenga, Menzo J. E., Barouch, Dan H.
Publicado em 2005

Neutralizing Antibodies and CD8(+) T Lymphocytes both Contribute to Immunity to Adenovirus Serotype 5 Vaccine Vectors

Por Sumida, Shawn M., Truitt, Diana M., Kishko, Michael G., Arthur, Janelle C., Jackson, Shawn S., Gorgone, Darci A., Lifton, Michelle A., Koudstaal, Wouter, Pau, Maria G., Kostense, Stefan, Havenga, Menzo J. E., Goudsmit, Jaap, Letvin, Norman L., Barouch, Dan H.
Publicado em 2004