Myeloid and Plasmacytoid Dendritic Cells Are Susceptible to Recombinant Adenovirus Vectors and Stimulate Polyfunctional Memory T Cell Responses

Although replication-incompetent recombinant adenovirus (rAd) type 5 is a potent vaccine vector for stimulating T and B cell responses, high seroprevalence of adenovirus type 5 (Ad5) within human populations may limit its clinical utility. Therefore, alternative adenovirus serotypes have been studie...

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Autores principales: Loré, Karin, Adams, William C., Havenga, Menzo J.E., Precopio, Melissa L., Holterman, Lennart, Goudsmit, Jaap, Koup, Richard A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365753/
https://ncbi.nlm.nih.gov/pubmed/17641038
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