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Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4(+) T cells

Dendritic cells (DCs) are essential antigen-presenting cells for the induction of T cell immunity against pathogens such as human immunodeficiency virus (HIV)-1. At the same time, HIV-1 replication is strongly enhanced in DC–T cell clusters, potentially undermining this process. We found that immatu...

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Detalhes bibliográficos
Main Authors: Loré, Karin, Smed-Sörensen, Anna, Vasudevan, Jayanand, Mascola, John R., Koup, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212038/
https://ncbi.nlm.nih.gov/pubmed/15967828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20042413
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