Human Plasmacytoid Dendritic Cells Efficiently Capture HIV-1 Envelope Glycoproteins via CD4 for Antigen Presentation

Advances in HIV-1 vaccine clinical trials and preclinical research indicate that the virus envelope glycoproteins (Env) are likely to be an essential component of a prophylactic vaccine. Efficient antigen uptake and presentation by dendritic cells (DCs) is important for strong CD4(+) T helper cell r...

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Publicado en:J Immunol
Autores principales: Sandgren, Kerrie J, Smed-Sörensen, Anna, Forsell, Mattias N, Soldemo, Martina, Adams, William C, Liang, Frank, Perbeck, Leif, Koup, Richard A, Wyatt, Richard T, Hedestam, Gunilla B Karlsson, Loré, Karin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4471340/
https://ncbi.nlm.nih.gov/pubmed/23729440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202489
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