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Avidity Binding of Human Adenovirus Serotypes 3 and 7 to the Membrane Cofactor CD46 Triggers Infection

The species B human adenoviruses (HAdVs) infect cells upon attaching to CD46 or desmoglein 2 (DSG-2) by one or several of their 12 fiber knob trimers (FKs). To test whether DSG-2 and CD46 simultaneously serve as virus receptors for adenovirus type 3 (Ad3), we performed individual and combined CD46/D...

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Detalhes bibliográficos
Main Authors: Trinh, Hung V., Lesage, Guillaume, Chennamparampil, Venus, Vollenweider, Benedikt, Burckhardt, Christoph J., Schauer, Stefan, Havenga, Menzo, Greber, Urs F., Hemmi, Silvio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264387/
https://ncbi.nlm.nih.gov/pubmed/22130529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06181-11
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