Trafficking of Antigen-Specific CD8+ T-Lymphocytes to Mucosal Surfaces Following Intramuscular Vaccination

A critical goal of vaccine development for a wide variety of pathogens is the induction of potent and durable mucosal immunity. However, it has been assumed that this goal would be difficult to achieve by systemic vaccination due to the anatomic and functional distinctness of the systemic and mucosa...

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Bibliographic Details
Main Authors: Kaufman, David R., Liu, Jinyan, Carville, Angela, Mansfield, Keith G., Havenga, Menzo J.E., Goudsmit, Jaap, Barouch, Dan H.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580672/
https://ncbi.nlm.nih.gov/pubmed/18768876
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