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A microbial expression system for high-level production of scFv HIV-neutralizing antibody fragments in Escherichia coli

Monoclonal antibodies (mABs) are of great biopharmaceutical importance for the diagnosis and treatment of diseases. However, their production in mammalian expression hosts usually requires extensive production times and is expensive. Escherichia coli has become a new platform for production of funct...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Appl Microbiol Biotechnol
मुख्य लेखकों: Petrus, Marloes L. C., Kiefer, Lukas A., Puri, Pranav, Heemskerk, Evert, Seaman, Michael S., Barouch, Dan H., Arias, Sagrario, van Wezel, Gilles P., Havenga, Menzo
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Springer Berlin Heidelberg 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851033/
https://ncbi.nlm.nih.gov/pubmed/31641814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-019-10145-1
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