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Synthetic customized scFv libraries

Libraries of antibody fragments displayed on filamentous phages have proved their value to generate human antibodies against virtually any target. We describe here a simple protocol to make large and diverse libraries based on a single or few frameworks. Diversity is introduced in the third hypervar...

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Bibliografske podrobnosti
Main Authors: Robin, Gautier, Martineau, Pierre
Format: Artigo
Jezik:Inglês
Izdano: Humana Press 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958428/
https://ncbi.nlm.nih.gov/pubmed/22907348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-974-7_6
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