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Synthetic customized scFv libraries
Libraries of antibody fragments displayed on filamentous phages have proved their value to generate human antibodies against virtually any target. We describe here a simple protocol to make large and diverse libraries based on a single or few frameworks. Diversity is introduced in the third hypervar...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Humana Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3958428/ https://ncbi.nlm.nih.gov/pubmed/22907348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-974-7_6 |
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