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A Novel Human scFv Library with Non-Combinatorial Synthetic CDR Diversity
The present work describes the construction and validation of a human scFv library with a novel design approach to synthetic complementarity determining region (CDR) diversification. The advantage of synthetic antibody libraries includes the possibility of exerting fine control over factors like fra...
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| 出版年: | PLoS One |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613135/ https://ncbi.nlm.nih.gov/pubmed/26484868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141045 |
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