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Nonspecificity in a nonimmune human scFv repertoire
Efforts to develop effective antibody therapeutics are frequently hampered by issues such as aggregation and nonspecificity, often only detected in late stages of the development process. In this study, we used a high throughput cross-reactivity assay to select nonspecific clones from a naïve human...
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| Veröffentlicht in: | MAbs |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5627588/ https://ncbi.nlm.nih.gov/pubmed/28910564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1356528 |
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