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Nonspecificity in a nonimmune human scFv repertoire

Efforts to develop effective antibody therapeutics are frequently hampered by issues such as aggregation and nonspecificity, often only detected in late stages of the development process. In this study, we used a high throughput cross-reactivity assay to select nonspecific clones from a naïve human...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:MAbs
Egile Nagusiak: Kelly, Ryan L., Zhao, Jessie, Le, Doris, Wittrup, K. Dane
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5627588/
https://ncbi.nlm.nih.gov/pubmed/28910564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1356528
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