Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium

Microtubule-associated protein tau associates with Src family tyrosine kinase Fyn and is tyrosine phosphorylated by Fyn. The presence of tyrosine phosphorylated tau in AD and the involvement of Fyn in AD has drawn attention to the tau-Fyn complex. In this study, a tau-Fyn double knockout (DKO) mouse...

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發表在:J Neurosci Res
Main Authors: Liu, Guanghao, Thangavel, Ramasamy, Rysted, Jacob, Kim, Yohan, Francis, Meghan B, Adams, Eric, Lin, Zhihong, Taugher, Rebecca J, Wemmie, John A, Usachev, Yuriy M, Lee, Gloria
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850396/
https://ncbi.nlm.nih.gov/pubmed/31452242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.24517
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