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Fyn-tau Ablation Modifies PTZ-Induced Seizures and Post-seizure Hallmarks of Early Epileptogenesis

Both Fyn and tau have been associated with neuronal hyperexcitability and neurotoxicity in many tauopathies, including Alzheimer's disease (AD). Individual genetic ablation of fyn or tau appears to be protective against aberrant excitatory neuronal activities in AD and epilepsy models. It is, h...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Putra, Marson, Puttachary, Sreekanth, Liu, Guanghao, Lee, Gloria, Thippeswamy, Thimmasettappa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7752812/
https://ncbi.nlm.nih.gov/pubmed/33363455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.592374
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