Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on calcium

Microtubule-associated protein tau associates with Src family tyrosine kinase Fyn and is tyrosine phosphorylated by Fyn. The presence of tyrosine phosphorylated tau in AD and the involvement of Fyn in AD has drawn attention to the tau-Fyn complex. In this study, a tau-Fyn double knockout (DKO) mouse...

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Bibliografiset tiedot
Julkaisussa:J Neurosci Res
Päätekijät: Liu, Guanghao, Thangavel, Ramasamy, Rysted, Jacob, Kim, Yohan, Francis, Meghan B, Adams, Eric, Lin, Zhihong, Taugher, Rebecca J, Wemmie, John A, Usachev, Yuriy M, Lee, Gloria
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850396/
https://ncbi.nlm.nih.gov/pubmed/31452242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.24517
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