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Fyn depletion ameliorates tau(P301L)-induced neuropathology

The Src family non-receptor tyrosine kinase Fyn has been implicated in neurodegeneration of Alzheimer’s disease through interaction with amyloid β (Aβ). However, the role of Fyn in the pathogenesis of primary tauopathies such as FTDP-17, where Aβ plaques are absent, is poorly understood. In the curr...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Liu, Guanghao, Fiock, Kimberly L., Levites, Yona, Golde, Todd E., Hefti, Marco M., Lee, Gloria
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7362472/
https://ncbi.nlm.nih.gov/pubmed/32665013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-00979-6
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