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Deletion of mitochondrial calcium uniporter incompletely inhibits calcium uptake and induction of the permeability transition pore in brain mitochondria
Ca(2+) influx into mitochondria is mediated by the mitochondrial calcium uniporter (MCU), whose identity was recently revealed as a 40-kDa protein that along with other proteins forms the mitochondrial Ca(2+) uptake machinery. The MCU is a Ca(2+)-conducting channel spanning the inner mitochondrial m...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6177608/ https://ncbi.nlm.nih.gov/pubmed/30154242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002926 |
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