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Deletion of mitochondrial calcium uniporter incompletely inhibits calcium uptake and induction of the permeability transition pore in brain mitochondria

Ca(2+) influx into mitochondria is mediated by the mitochondrial calcium uniporter (MCU), whose identity was recently revealed as a 40-kDa protein that along with other proteins forms the mitochondrial Ca(2+) uptake machinery. The MCU is a Ca(2+)-conducting channel spanning the inner mitochondrial m...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Hamilton, James, Brustovetsky, Tatiana, Rysted, Jacob E., Lin, Zhihong, Usachev, Yuriy M., Brustovetsky, Nickolay
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177608/
https://ncbi.nlm.nih.gov/pubmed/30154242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002926
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