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Role of cyclophilin D-dependent mitochondrial permeability transition in glutamate-induced calcium deregulation and excitotoxic neuronal death

In the present study we tested the hypothesis that the cyclophilin D-dependent (CyD) mitochondrial permeability transition (CyD-mPT) plays an important role in glutamate-triggered delayed calcium deregulation (DCD) and excitotoxic neuronal death. We used cultured cortical neurons from wild-type C57B...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Viacheslav, Brustovetsky, Tatiana, Brustovetsky, Nickolay
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710407/
https://ncbi.nlm.nih.gov/pubmed/19236863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2009.02.007
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