The transcriptome of CMML monocytes is highly inflammatory and reflects leukemia-specific and age-related alterations

Chronic myelomonocytic leukemia (CMML) is an aggressive myeloid neoplasm of older individuals characterized by persistent monocytosis. Somatic mutations in CMML are heterogeneous and only partially explain the variability in clinical outcomes. Recent data suggest that cardiovascular morbidity is inc...

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Vydáno v:Blood Adv
Hlavní autoři: Franzini, Anca, Pomicter, Anthony D., Yan, Dongqing, Khorashad, Jamshid S., Tantravahi, Srinivas K., Than, Hein, Ahmann, Jonathan M., O’Hare, Thomas, Deininger, Michael W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2019
Témata:
Myeloid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849944/
https://ncbi.nlm.nih.gov/pubmed/31648319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000585
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