The transcriptome of CMML monocytes is highly inflammatory and reflects leukemia-specific and age-related alterations

Chronic myelomonocytic leukemia (CMML) is an aggressive myeloid neoplasm of older individuals characterized by persistent monocytosis. Somatic mutations in CMML are heterogeneous and only partially explain the variability in clinical outcomes. Recent data suggest that cardiovascular morbidity is inc...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Franzini, Anca, Pomicter, Anthony D., Yan, Dongqing, Khorashad, Jamshid S., Tantravahi, Srinivas K., Than, Hein, Ahmann, Jonathan M., O’Hare, Thomas, Deininger, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849944/
https://ncbi.nlm.nih.gov/pubmed/31648319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000585
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