SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

We analyzed the mutational hotspot region of SRSF2 (Pro95) in 275 cases with chronic myelomonocytic leukemia (CMML). In addition, ASXL1, CBL, EZH2, JAK2V617F, KRAS, NRAS, RUNX1, and TET2 mutations were investigated in subcohorts. Mutations in SRSF2 (SRSF2mut) were detected in 47% (129 of 275) of all...

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Dades bibliogràfiques
Autors principals: Meggendorfer, Manja, Roller, Andreas, Haferlach, Torsten, Eder, Christiane, Dicker, Frank, Grossmann, Vera, Kohlmann, Alexander, Alpermann, Tamara, Yoshida, Kenichi, Ogawa, Seishi, Koeffler, H. Phillip, Kern, Wolfgang, Haferlach, Claudia, Schnittger, Susanne
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580040/
https://ncbi.nlm.nih.gov/pubmed/22919025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-404863
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