SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

We analyzed the mutational hotspot region of SRSF2 (Pro95) in 275 cases with chronic myelomonocytic leukemia (CMML). In addition, ASXL1, CBL, EZH2, JAK2V617F, KRAS, NRAS, RUNX1, and TET2 mutations were investigated in subcohorts. Mutations in SRSF2 (SRSF2mut) were detected in 47% (129 of 275) of all...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Meggendorfer, Manja, Roller, Andreas, Haferlach, Torsten, Eder, Christiane, Dicker, Frank, Grossmann, Vera, Kohlmann, Alexander, Alpermann, Tamara, Yoshida, Kenichi, Ogawa, Seishi, Koeffler, H. Phillip, Kern, Wolfgang, Haferlach, Claudia, Schnittger, Susanne
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2012
Gaiak:
Myeloid Neoplasia
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580040/
https://ncbi.nlm.nih.gov/pubmed/22919025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-404863
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