SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

We analyzed the mutational hotspot region of SRSF2 (Pro95) in 275 cases with chronic myelomonocytic leukemia (CMML). In addition, ASXL1, CBL, EZH2, JAK2V617F, KRAS, NRAS, RUNX1, and TET2 mutations were investigated in subcohorts. Mutations in SRSF2 (SRSF2mut) were detected in 47% (129 of 275) of all...

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Detalhes bibliográficos
Main Authors: Meggendorfer, Manja, Roller, Andreas, Haferlach, Torsten, Eder, Christiane, Dicker, Frank, Grossmann, Vera, Kohlmann, Alexander, Alpermann, Tamara, Yoshida, Kenichi, Ogawa, Seishi, Koeffler, H. Phillip, Kern, Wolfgang, Haferlach, Claudia, Schnittger, Susanne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580040/
https://ncbi.nlm.nih.gov/pubmed/22919025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-404863
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