SRSF2 mutations in 275 cases with chronic myelomonocytic leukemia (CMML)

We analyzed the mutational hotspot region of SRSF2 (Pro95) in 275 cases with chronic myelomonocytic leukemia (CMML). In addition, ASXL1, CBL, EZH2, JAK2V617F, KRAS, NRAS, RUNX1, and TET2 mutations were investigated in subcohorts. Mutations in SRSF2 (SRSF2mut) were detected in 47% (129 of 275) of all...

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Detaylı Bibliyografya
Asıl Yazarlar: Meggendorfer, Manja, Roller, Andreas, Haferlach, Torsten, Eder, Christiane, Dicker, Frank, Grossmann, Vera, Kohlmann, Alexander, Alpermann, Tamara, Yoshida, Kenichi, Ogawa, Seishi, Koeffler, H. Phillip, Kern, Wolfgang, Haferlach, Claudia, Schnittger, Susanne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2012
Konular:
Myeloid Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580040/
https://ncbi.nlm.nih.gov/pubmed/22919025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-404863
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