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The transcriptome of CMML monocytes is highly inflammatory and reflects leukemia-specific and age-related alterations

Chronic myelomonocytic leukemia (CMML) is an aggressive myeloid neoplasm of older individuals characterized by persistent monocytosis. Somatic mutations in CMML are heterogeneous and only partially explain the variability in clinical outcomes. Recent data suggest that cardiovascular morbidity is inc...

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發表在:Blood Adv
Main Authors: Franzini, Anca, Pomicter, Anthony D., Yan, Dongqing, Khorashad, Jamshid S., Tantravahi, Srinivas K., Than, Hein, Ahmann, Jonathan M., O’Hare, Thomas, Deininger, Michael W.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849944/
https://ncbi.nlm.nih.gov/pubmed/31648319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000585
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