ATIM-27. TUMOR MUTATIONAL BURDEN PREDICTS RESPONSE TO ONCOLYTIC POLIO/RHINOVIRUS RECOMBINANT (PVSRIPO) IN MALIGNANT GLIOMA PATIENTS: ASSESSMENT OF TRANSCRIPTIONAL AND IMMUNOLOGICAL CORRELATES

BACKGROUND: The live attenuated oral poliovirus vaccine was modified to contain a heterologous internal ribosomal entry site stemming from human rhinovirus type 2, creating PVSRIPO. PVSRIPO recognizes CD155, an oncofetal cell adhesion molecule and tumor antigen widely expressed ectopically in malign...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Gromeier, Matthias, Brown, Michael, Beuabier, Nike, Yan, Hai, He, Yiping, Zhang, Gao, Desjardins, Annick, Herndon, James, Bolognesi, Dani, Friedman, Allan, Friedman, Henry, McSherry, Frances, Lin, Xiang, Wei, Zhi, Nair, Smita, Peters, Katherine, Randazzo, Dina, Sampson, John, McLendon, Roger, Bigner, Darell, Ashley, David
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
Предметы:
Adult Clinical Trials–Immunologic
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847607/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.026
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы