ATIM-27. TUMOR MUTATIONAL BURDEN PREDICTS RESPONSE TO ONCOLYTIC POLIO/RHINOVIRUS RECOMBINANT (PVSRIPO) IN MALIGNANT GLIOMA PATIENTS: ASSESSMENT OF TRANSCRIPTIONAL AND IMMUNOLOGICAL CORRELATES

BACKGROUND: The live attenuated oral poliovirus vaccine was modified to contain a heterologous internal ribosomal entry site stemming from human rhinovirus type 2, creating PVSRIPO. PVSRIPO recognizes CD155, an oncofetal cell adhesion molecule and tumor antigen widely expressed ectopically in malign...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Gromeier, Matthias, Brown, Michael, Beuabier, Nike, Yan, Hai, He, Yiping, Zhang, Gao, Desjardins, Annick, Herndon, James, Bolognesi, Dani, Friedman, Allan, Friedman, Henry, McSherry, Frances, Lin, Xiang, Wei, Zhi, Nair, Smita, Peters, Katherine, Randazzo, Dina, Sampson, John, McLendon, Roger, Bigner, Darell, Ashley, David
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Adult Clinical Trials–Immunologic
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847607/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.026
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars