AT-21 FINAL RESULTS OF A PHASE 1 TRIAL OF AN ONCOLYTIC POLIO/RHINOVIRUS RECOMBINANT (PVSRIPO) AGAINST RECURRENT GLIOBLASTOMA (GBM)

BACKGROUND: PVSRIPO is the live attenuated, oral (SABIN) serotype 1 poliovirus vaccine containing a heterologous internal ribosomal entry site stemming from human rhinovirus type 2. PVSRIPO recognizes nectin-like molecule-5, an oncofetal cell adhesion molecule and tumor antigen widely expressed ecto...

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Autori principali: Desjardins, Annick, Sampson, John, Peters, Katherine, Vlahovic, Gordana, Threatt, Stevie, Herndon, James, Boulton, Susan, Lally-Goss, Denise, McSherry, Frances, Lipp, Eric, Friedman, Allan, Friedman, Henry, Bigner, Darell, Gromeier, Matthias
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217799/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou237.21
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