ATIM-27. TUMOR MUTATIONAL BURDEN PREDICTS RESPONSE TO ONCOLYTIC POLIO/RHINOVIRUS RECOMBINANT (PVSRIPO) IN MALIGNANT GLIOMA PATIENTS: ASSESSMENT OF TRANSCRIPTIONAL AND IMMUNOLOGICAL CORRELATES

BACKGROUND: The live attenuated oral poliovirus vaccine was modified to contain a heterologous internal ribosomal entry site stemming from human rhinovirus type 2, creating PVSRIPO. PVSRIPO recognizes CD155, an oncofetal cell adhesion molecule and tumor antigen widely expressed ectopically in malign...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: Gromeier, Matthias, Brown, Michael, Beuabier, Nike, Yan, Hai, He, Yiping, Zhang, Gao, Desjardins, Annick, Herndon, James, Bolognesi, Dani, Friedman, Allan, Friedman, Henry, McSherry, Frances, Lin, Xiang, Wei, Zhi, Nair, Smita, Peters, Katherine, Randazzo, Dina, Sampson, John, McLendon, Roger, Bigner, Darell, Ashley, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Adult Clinical Trials–Immunologic
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847607/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.026
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk