CBMT-23. NON-CANONICAL FUNCTIONS OF TERT IN GLIOBLASTOMA

Telomerase is an enzyme with a catalytic subunit, telomerase reverse transcriptase (TERT), that is in charge of telomere elongation in the nucleus. Promotor region of TERT is commonly mutated across cancers, especially in glioblastoma (GBM) with over 80% frequency. In the absence of any effective mo...

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Udgivet i:Neuro Oncol
Main Authors: Ferdosi, Shayesteh, Taylor, Brett, Bollam, Saumya, Gokhale, Vijay, Hurley, Laurence, Dhruv, Harshil, Berens, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Cell Biology and Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847136/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.145
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