CBMT-23. NON-CANONICAL FUNCTIONS OF TERT IN GLIOBLASTOMA

Telomerase is an enzyme with a catalytic subunit, telomerase reverse transcriptase (TERT), that is in charge of telomere elongation in the nucleus. Promotor region of TERT is commonly mutated across cancers, especially in glioblastoma (GBM) with over 80% frequency. In the absence of any effective mo...

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Publicado en:Neuro Oncol
Autores principales: Ferdosi, Shayesteh, Taylor, Brett, Bollam, Saumya, Gokhale, Vijay, Hurley, Laurence, Dhruv, Harshil, Berens, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
Materias:
Cell Biology and Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847136/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.145
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