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CBMT-23. NON-CANONICAL FUNCTIONS OF TERT IN GLIOBLASTOMA

Telomerase is an enzyme with a catalytic subunit, telomerase reverse transcriptase (TERT), that is in charge of telomere elongation in the nucleus. Promotor region of TERT is commonly mutated across cancers, especially in glioblastoma (GBM) with over 80% frequency. In the absence of any effective mo...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Ferdosi, Shayesteh, Taylor, Brett, Bollam, Saumya, Gokhale, Vijay, Hurley, Laurence, Dhruv, Harshil, Berens, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847136/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.145
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