Načítá se...

CBMT-21. TERT PROMOTER-MUTANT GLIOBLASTOMAS EXHIBIT DEPENDENCY ON TELOMERASE

TERT promoter mutations are among the most common somatic alterations in cancer and they occur in about 80% of IDH-wildtype glioblastomas. TERT promoter mutations were found to reactivate telomerase by providing a novel binding site for the GABP transcription factor. While the effects of telomerase...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Neuro Oncol
Hlavní autoři: Aquilanti, Elisa, Baird, Duncan, Watson, Jacqueline, Meyerson, Matthew
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6846884/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.143
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!