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Methods to identify and optimize small molecules interacting with RNA (SMIRNAs)

RNAs, particularly noncoding RNAs (ncRNAs), are becoming increasingly important therapeutic targets, because they are causative and antagonists of human disease. Indeed, aberrant RNA structural elements and expression deregulate biological processes. In this review, we describe methodologies to disc...

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Bibliografski detalji
Izdano u:Drug Discov Today
Glavni autori: Ursu, Andrei, Vézina-Dawod, Simon, Disney, Matthew D.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6842402/
https://ncbi.nlm.nih.gov/pubmed/31356880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2019.06.019
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