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Identifying and validating small molecules interacting with RNA (SMIRNAs)

High throughput sequencing has revolutionized our ability to identify aberrant RNA expression and mutations that cause or contribute to disease. These data can be used directly to design oligonucleotide-based modalities using Watson-Crick pairing to target unstructured regions in an RNA. A complemen...

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Disney, Matthew D., Velagapudi, Sai Pradeep, Li, Yue, Costales, Matthew G., Childs-Disney, Jessica L.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628145/
https://ncbi.nlm.nih.gov/pubmed/31239057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.04.027
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