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Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit

A hypoxic state is critical to the metastatic and invasive characteristics of cancer. Numerous pathways play critical roles in cancer maintenance, many of which include noncoding RNAs such as microRNA (miR)-210 that regulates hypoxia inducible factors (HIFs). Herein, we describe the identification o...

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Bibliografiska uppgifter
I publikationen:J Am Chem Soc
Huvudupphovsmän: Costales, Matthew G., Haga, Christopher L., Velagapudi, Sai Pradeep, Childs-Disney, Jessica L., Phinney, Donald G., Disney, Matthew D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810126/
https://ncbi.nlm.nih.gov/pubmed/28240549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11273
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