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Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit

A hypoxic state is critical to the metastatic and invasive characteristics of cancer. Numerous pathways play critical roles in cancer maintenance, many of which include noncoding RNAs such as microRNA (miR)-210 that regulates hypoxia inducible factors (HIFs). Herein, we describe the identification o...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Costales, Matthew G., Haga, Christopher L., Velagapudi, Sai Pradeep, Childs-Disney, Jessica L., Phinney, Donald G., Disney, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810126/
https://ncbi.nlm.nih.gov/pubmed/28240549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11273
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