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Design of a small molecule against an oncogenic noncoding RNA

The design of precision, preclinical therapeutics from sequence is difficult, but advances in this area, particularly those focused on rational design, could quickly transform the sequence of disease-causing gene products into lead modalities. Herein, we describe the use of Inforna, a computational...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Velagapudi, Sai Pradeep, Cameron, Michael D., Haga, Christopher L., Rosenberg, Laura H., Lafitte, Marie, Duckett, Derek R., Phinney, Donald G., Disney, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889373/
https://ncbi.nlm.nih.gov/pubmed/27170187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523975113
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