Design of small molecules targeting RNA structure from sequence

The design and discovery of small molecule medicines has largely been focused on a small number of druggable protein families. A new paradigm is emerging, however, in which small molecules exert a biological effect by interacting with RNA, both to study human disease biology and provide lead therape...

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Bibliografske podrobnosti
izdano v:Chem Soc Rev
Main Authors: Ursu, Andrei, Childs-Disney, Jessica L., Andrews, Ryan J., O’Leary, Collin A., Meyer, Samantha M., Angelbello, Alicia J., Moss, Walter N., Disney, Matthew D.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707016/
https://ncbi.nlm.nih.gov/pubmed/32935689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0cs00455c
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