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Gini coefficients as a single value metric to define chemical probe selectivity
Selectivity is a key requirement of high-quality chemical probes and lead medicines, however methods to quantify and compare the selectivity of small molecules have not been standardized across the field. Herein, we discuss the origins and use of a comprehensive, single value term to quantify select...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | ACS Chem Biol |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7442733/ https://ncbi.nlm.nih.gov/pubmed/32568503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00486 |
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