Llwytho...

Gini coefficients as a single value metric to define chemical probe selectivity

Selectivity is a key requirement of high-quality chemical probes and lead medicines, however methods to quantify and compare the selectivity of small molecules have not been standardized across the field. Herein, we discuss the origins and use of a comprehensive, single value term to quantify select...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:ACS Chem Biol
Prif Awduron: Ursu, Andrei, Childs-Disney, Jessica L., Angelbello, Alicia J., Costales, Matthew G., Meyer, Samantha M., Disney, Matthew D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442733/
https://ncbi.nlm.nih.gov/pubmed/32568503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00486
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