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Methods to enable the design of bioactive small molecules targeting RNA

RNA is an immensely important target for small molecule therapeutics or chemical probes of function. However, methods that identify, annotate, and optimize RNA-small molecule interactions that could enable the design of compounds that modulate RNA function are in their infancies. This review describ...

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Detalhes bibliográficos
Main Authors: Disney, Matthew D., Yildirim, Ilyas, Childs-Disney, Jessica L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020623/
https://ncbi.nlm.nih.gov/pubmed/24357181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob42023j
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