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Approaches to Validate and Manipulate RNA Targets with Small Molecules in Cells

RNA has become an increasingly important target for therapeutic interventions and for chemical probes that dissect and manipulate its cellular function. Emerging targets include human RNAs that have been shown to directly cause cancer, metabolic disorders, and genetic disease. In this review, we des...

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Podrobná bibliografie
Vydáno v:Annu Rev Pharmacol Toxicol
Hlavní autoři: Childs-Disney, Jessica L., Disney, Matthew D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876813/
https://ncbi.nlm.nih.gov/pubmed/26514201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010715-103910
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