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Structural basis for α-bungarotoxin insensitivity of neuronal nicotinic acetylcholine receptors
The ten types of nicotinic acetylcholine receptor α-subunits show substantial sequence homology, yet some types confer high affinity for α-bungarotoxin, whereas others confer negligible affinity. Combining sequence alignments with structural data reveals three residues unique to α-toxin-refractory α...
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| Udgivet i: | Neuropharmacology |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6842095/ https://ncbi.nlm.nih.gov/pubmed/31163179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2019.05.037 |
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