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Mice Deficient in the α7 Neuronal Nicotinic Acetylcholine Receptor Lack α-Bungarotoxin Binding Sites and Hippocampal Fast Nicotinic Currents

The α7 subunit of the neuronal nicotinic acetylcholine receptor (nAChR) is abundantly expressed in hippocampus and is implicated in modulating neurotransmitter release and in binding α-bungarotoxin (α-BGT). A null mutation for the α7 subunit was prepared by deleting the last three exons of the gene....

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Publicat a:J Neurosci
Autors principals: Orr-Urtreger, Avi, Göldner, Finn M., Saeki, Mayuko, Lorenzo, Isabel, Goldberg, Leah, De Biasi, Mariella, Dani, John A., Patrick, James W., Beaudet, Arthur L.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573618/
https://ncbi.nlm.nih.gov/pubmed/9364063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-23-09165.1997
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