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Stoichiometry for α-bungarotoxin block of α7 acetylcholine receptors
α-Bungarotoxin (α-Btx) binds to the five agonist binding sites on the homopentameric α7-acetylcholine receptor, yet the number of bound α-Btx molecules required to prevent agonist-induced channel opening remains unknown. To determine the stoichiometry for α-Btx blockade, we generate receptors compri...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Pub. Group
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4544739/ https://ncbi.nlm.nih.gov/pubmed/26282895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9057 |
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