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Stoichiometry for drug potentiation of a pentameric ion channel
Drug modulation of ion channels is a powerful means to alter physiological responses for therapeutic benefit, yet the structural bases of modulation remain poorly understood. Here we study potentiation of nicotinic α7 acetylcholine receptors, which are emerging drug targets in several neurological d...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3631634/ https://ncbi.nlm.nih.gov/pubmed/23576748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301909110 |
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